Antileukemic activity of the chemical constituents from Scutellaria barbata D. Don
نویسندگان
چکیده
منابع مشابه
Anti-angiogenic effects of total flavonoids from Scutellaria barbata D. Don
Background: Angiogenesis is closely related to the growth, invasion and metastasis of the tumor, also anticancer therapy key targets. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is being used for treatment of many diseases including cancer. However, the antitumor molecular mechanism of S. barbata was unclear. This study is aimed to investigate the inhibitory effect ...
متن کاملOptimization of ultrasonic extraction of alkaloids from Scutellaria barbata D. Don using response surface methodology
Based on a BoxBehnken design,response surface methodology was used to optimize the effects of processing parameters of extraction from Scutellaria barbata on total alkaloids yield. Three independent variables such as extraction time (X1), liquid-solid ratio (X2) and ultrasonic frequency (X3) were study. The P-value indicated that both extraction time (X1) and ultrasonic frequency (X3) had signi...
متن کاملAnti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
BACKGROUND Angiogenesis is closely related to the growth, invasion and metastasis of tumors, also considered as the key target of anticancer therapy. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is being used to treat various diseases, including cancer. However, the antitumor molecular mechanism of S. barbata was still unclear. This study aimed to investigate the inh...
متن کاملThe anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells
Lung cancer, with a poor prognosis and resistance to chemotherapy, is the most common malignant tumor and has the highest mortality rate worldwide. Scutellaria barbata D. Don (SB), which is derived from the dried whole plant of Labiatae, is a well-known anti-inflammatory and anti-cancer herb. The aim of this study was to examine the anti-cancer effects and precise regulatory mechanisms of SB in...
متن کاملTwo new phenols from Scutellaria barbata.
Two new phenols, 2(S)-2',7-dihydroxy-5,8-dimethoxyflavanone and (S)-2-(4-hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one, were isolated from the ethanol extract of Scutellaria barbata. Their structures were elucidated on the basis of spectroscopic analysis.
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ژورنال
عنوان ژورنال: Acta Chromatographica
سال: 2017
ISSN: 1233-2356,2083-5736
DOI: 10.1556/1326.2017.29.3.10